Pre_GI: SWBIT SVG BLASTP

Query: NC_013316:3056925 Clostridium difficile R20291, complete genome

Lineage: Peptoclostridium difficile; Peptoclostridium; Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium difficile R20291 was isolated in Stoke Mandeville Hospital, UK in 2006 and is closely related to the North American hypervirulent BI strains. Clostridium difficile, a Gram-positive, spore-forming anaerobic bacterium, is the leading cause of infectious diarrhea among patients in hospitals worldwide, causing C. difficile infection (CDI). An important nosocomial pathogen, it is frequently associated with antibiotic treatment and causes diseases ranging from antibiotic-associated diarrhea to life-threatening pseudomembraneous colitis.

Subject: NC_012883:104987 Thermococcus sibiricus MM 739, complete genome

Lineage: Thermococcus sibiricus; Thermococcus; Thermococcaceae; Thermococcales; Euryarchaeota; Archaea

General Information: Thermococcus sibiricus is a hyperthermophilic anaerobic archaeon isolated from a well of the never flooded oil-bearing Jurassic horizon of the high-temperature Samotlor oil reservoir (Western Siberia). The organism is indigenous to the reservoir and survived over geologic time by metabolizing buried organic matter from the original oceanic sediment.