Pre_GI: SWBIT SVG BLASTP

Query: NC_013316:1081044 Clostridium difficile R20291, complete genome

Lineage: Peptoclostridium difficile; Peptoclostridium; Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium difficile R20291 was isolated in Stoke Mandeville Hospital, UK in 2006 and is closely related to the North American hypervirulent BI strains. Clostridium difficile, a Gram-positive, spore-forming anaerobic bacterium, is the leading cause of infectious diarrhea among patients in hospitals worldwide, causing C. difficile infection (CDI). An important nosocomial pathogen, it is frequently associated with antibiotic treatment and causes diseases ranging from antibiotic-associated diarrhea to life-threatening pseudomembraneous colitis.

Subject: NC_003413:128228 Pyrococcus furiosus DSM 3638, complete genome

Lineage: Pyrococcus furiosus; Pyrococcus; Thermococcaceae; Thermococcales; Euryarchaeota; Archaea

General Information: This strain was isolated from a shallow marine solfataric (volcanic area that gives off sulfuric gases) region at Vulcano Island, Italy. This organism is a strictly anaerobic, hyperthermophilic archaeon. Growth occurs at temperatures between 67 and 103 degrees C, with optimal growth at 100 degrees C and a pH of 7.0. This organism is highly motile due to a bundle of flagella.