Query: NC_013316:81969 Clostridium difficile R20291, complete genome
Lineage: Peptoclostridium difficile; Peptoclostridium; Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria
General Information: Clostridium difficile R20291 was isolated in Stoke Mandeville Hospital, UK in 2006 and is closely related to the North American hypervirulent BI strains. Clostridium difficile, a Gram-positive, spore-forming anaerobic bacterium, is the leading cause of infectious diarrhea among patients in hospitals worldwide, causing C. difficile infection (CDI). An important nosocomial pathogen, it is frequently associated with antibiotic treatment and causes diseases ranging from antibiotic-associated diarrhea to life-threatening pseudomembraneous colitis.
Subject: NC_010981:1243888 Wolbachia pipientis, complete genome
Lineage: Wolbachia endosymbiont of Culex quinquefasciatus; Wolbachia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria
General Information: This bacterial endosymbiont was isolated from the preblastoderm embryos of the Pel strain of Culex quinquefasciatus mosquitoes. This group of bacteria are associated with a variety of invertebrate species, some as pathogens, some in a symbiotic or other type of relationship. Typically these organisms are transmitted maternally from mother to daughter transovarially (through the egg) although these bacteria can affect their hosts reproductive capabilities in order to enhance transmission. The net outcome is the increase of hosts carrying the bacteria in the next generation, thereby increasing transmission.