Pre_GI: SWBIT SVG BLASTP

Query: NC_013315:2505792 Clostridium difficile CD196 chromosome, complete genome

Lineage: Peptoclostridium difficile; Peptoclostridium; Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria

General Information: Isolated from a single patient with pseudomembranous colitis in a Paris hospital in 1985. Clostridium difficile, a Gram-positive, spore-forming anaerobic bacterium, is the leading cause of infectious diarrhea among patients in hospitals worldwide, causing C. difficile infection (CDI). An important nosocomial pathogen, it is frequently associated with antibiotic treatment and causes diseases ranging from antibiotic-associated diarrhea to life-threatening pseudomembraneous colitis.

Subject: NC_018664:1279950 Clostridium acidurici 9a chromosome, complete genome

Lineage: Gottschalkia acidurici; Gottschalkia; ; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium acidiurici is an obligate anaerobic Gram-positive bacterium that is motile and spore-forming. It can be isolated from almost every soil but can also be found in the intestinal tract of birds. It is able to use purines like uric acid as sole carbon, nitrogen and energy source to build ammonia, carbon dioxide and acetic acid. Unlike most other Clostridia it is a specialist and not able to grow on sugars or different other substrates than purines.