Query: NC_013216:293571 Desulfotomaculum acetoxidans DSM 771, complete genome Lineage: Desulfotomaculum acetoxidans; Desulfotomaculum; Peptococcaceae; Clostridiales; Firmicutes; Bacteria General Information: Isolation: Pig waste in Gottingen, Germany; Temp: Mesophile; Temp: 37C; Habitat: Animal intestinal microflora, Fresh water. Desulfotomaculum acetoxidans has been isolated from fresh or seawater sediment and animal wastes. This organism is able to oxidize acetate to carbon dioxide with the production of hydrogen sulfide.
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General Information: This strain is the first isolate of Ehrlichia chaffeensis, which was obtained from a patient on an army base in Arkansas, USA in 1990. Causes disease in humans. This organism is an obligate intracellular pathogen that exists within vacuoles in the cytoplasm of monocytes or granulocytes. Transferred during an insect (tick) bite, it can cause disease in humans (human monocytic ehrlichiosis) and can reside in several other animals and is a problem in immunocompromised patients. The bacterium inhibits phagosome-lysozome fusion as well as programmed cell death (apoptosis) of the host cell, similar to what is observed with Anaplasma phagocytophilum.