Query: NC_013205:1123280 Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446, Lineage: Alicyclobacillus acidocaldarius; Alicyclobacillus; Alicyclobacillaceae; Bacillales; Firmicutes; Bacteria General Information: Isolation: Yellowstone National Park, acid hot; Country: USA; Temp: Thermophile; Temp: 60C. Alicyclobacillus acidocaldarius, formerly Bacillus acidocaldarius was first isolated from an acidic creek in Yellowston National Park and grows at a pH of 3.6. This organism is both thermophilic and acidophilic and produces heat and acid stable enzymes, such as amylase and esterase, which may be important in industry.
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General Information: Causes glanders in horses. This organism is rarely associated with human infection, and is more commonly seen in domesticated animals such as horses, donkeys, and mules where it causes glanders, a disease first described by Aristotle. The pathogen is host-adapted and is not found in the environment outside of its host. Rapid-onset pneumonia, bacteremia (spread of the organism through the blood), pustules, and death are common outcomes during infection. No vaccine exists for this potentially dangerous organism.