Pre_GI: SWBIT SVG BLASTP

Query: NC_013203:1447340 Atopobium parvulum DSM 20469, complete genome

Lineage: Atopobium parvulum; Atopobium; Coriobacteriaceae; Coriobacteriales; Actinobacteria; Bacteria

General Information: Temp: Mesophile; Temp: 37 - 45C; Habitat: Host, Human airways, Oral microflora. A member of the lactic acid group of bacteria, commonly isolated from the gingival crevices of the human oral cavity. This organism has also occasionally been isolated from dental abscesses.

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Subject: NC_008343:823093 Granulibacter bethesdensis CGDNIH1, complete genome

Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria

General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.