Query: NC_013194:3984377 Candidatus Accumulibacter phosphatis clade IIA str. UW-1, complete Lineage: Accumulibacter phosphatis; Accumulibacter; ; ; Proteobacteria; Bacteria General Information: Isolation: enhanced biological phosphorus removal; Country: USA; Temp: Mesophile; Habitat: Sediment, Sludge. Candidatus Accumulibactor phosphatis is a polyphosphate-accumulating, aerobic, Gram-negative bacterium that has been identified in enhanced biological phosphorus removal (EBPR) wastewater treatment systems. Removal of phosphorus from wastewater is important to avoid eutrophication (excess nutrients) in surface waters.
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General Information: The B serogroup is responsible for many of the meningitis outbreaks in the developed world. This strain was isolated from a case of invasive infection. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.