Query: NC_013171:75110 Anaerococcus prevotii DSM 20548, complete genome Lineage: Anaerococcus prevotii; Anaerococcus; Clostridiales Family XI; Clostridiales; Firmicutes; Bacteria General Information: Isolation: Human plasma; Temp: Mesophile; Temp: 37C; Habitat: Host, Mouth microflora, Skin microflora. Anaerococcus prevotii, formerly Peptostreptococcus prevotii, is a member of the normal human gastrointestinal tract. However, it can be isolated from abscesses and other infections and may be considered an opportunistic pathogen.
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General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.