Pre_GI: SWBIT SVG BLASTP

Query: NC_013170:277321 Cryptobacterium curtum DSM 15641, complete genome

Lineage: Cryptobacterium curtum; Cryptobacterium; Coriobacteriaceae; Coriobacteriales; Actinobacteria; Bacteria

General Information: Isolation: Periodontal pocket of an adult patient; Temp: Mesophile; Temp: 37C; Habitat: Host, Human oral microflora. This organism has been isolated from periodontal lesions and may play an important role in those infections.

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Subject: NC_004311:1096649 Brucella suis 1330 chromosome II, complete sequence

Lineage: Brucella suis; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: A swine isolate. Causes brucellosis, infectious abortions, fevers. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism is a swine-specific Brucella. It causes infectious abortions in animals and a systemic, febrile (feverish) illness in humans. Brucella suis is considered a potential bioterrorism agent and was the first pathogenic organism to be weaponized by the USA.