Query: NC_013159:2098500 Saccharomonospora viridis DSM 43017, complete genome Lineage: Saccharomonospora viridis; Saccharomonospora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria General Information: This organism has been implicated in a range of hypersensitivity pneumonitides, including farmer's lung disease. Symptoms of the disease develop in susceptible individuals following the inhalation of spores from overheated materials such as moldy hay and bagasse, or from forced-air heating and humidification systems. Prolonged exposure to the antigens results in acute respiratory distress which may lead to irreversible lung damage. Saccharomonospora viridis DSM 43017 was isolated from Irish peat and was originally classified as Thermomonospora viridis.
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General Information: This organism was discovered in 1819 by Bizio who named the organism after the Italian physicist Serrati. It was considered a nonpathogenic organism until late in the 20th century, although pathogenicity was noted as early as 1913. Serratia marcescens is an opportunistic human pathogen that is increasingly associated with life-threatening hospital-acquired infections. It is an environmental organism that has a broad host range, and is capable of infecting vertebrates and invertebrates, as well as plants. In humans, Serratia marcescens can cause meningitis (inflammation of the membrane surrounding the brain and spinal cord), endocarditis (inflammation of heart muscle) and pyelonephritis (inflammation of the kidneys). Many strains are resistant to multiple antibiotics. Environmental isolates are noted by production of the red pigment prodigiosin.