Query: NC_013093:1 Actinosynnema mirum DSM 43827, complete genome Lineage: Actinosynnema mirum; Actinosynnema; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria General Information: Isolation: Blade of grass from Raritan River NJ; Country: USA; Temp: Mesophile; Temp: 10-30C; Habitat: Soil. This bacterium produces the antibiotic nocardicin A. Soil dwelling, nonmotile aerobe it has fine hyphae which form aerial and substrate mycelia. Motile spores are borne on synnemata, compact groups of erect hyphae. It produces nocardicin antibiotics and is able to inhibit growth of several Gram-positive bacteria as well as some filamentous fungi and yeasts.
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General Information: A serum-resistant streptomycin-resistant proline-requiring strain isolated from a patient with disseminated gonococcal infections. Causes gonorrhea. One of two pathogenic Neisseria, this species causes the sexually transmitted disease (STD) gonorrhea, which is the leading reportable STD in adults in the USA. This human-specific organism colonizes and invades the mucosal surface of the urogenital epithelium, crosses the epithelial barrier, and ends up multiplying on the basement membrane. The Opa proteins are responsible for the opaque colony phenotype due to the tight junctions between adjacent Neisseria, and are also responsible for tight adherence to host cells. This organism, like Neisseria meningitidis, is also naturally competent for DNA uptake.