Query: NC_013009:608515 Neorickettsia risticii str. Illinois, complete genome
Lineage: Neorickettsia risticii; Neorickettsia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria
General Information: Neorickettsia risticii str. Illinois was isolated from horse blood in Maryland, USA. Neorickettsia risticii, formerly Ehrlichia risticii, is an obligate intracellular bacterium related to the Rickettsia. It can be transmitted from flukes that infest snails, fish or aquatic insects to horses by ingestion. This organism causes Potomac horse fever, also knows as equine monocytic ehrlichiosis, an acute diarrheal disease.
Subject: NC_012633:169444 Rickettsia africae ESF-5, complete genome
Lineage: Rickettsia africae; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria
General Information: This organism was isolated from a cattle tick, Amblyomma variegatum, collected in Ethiopia. This organism, a member of the spotted fever group of the Rickettsiales, is found in sub-Saharan Africa and the Caribbean. Rickettsia africae causes a flu-like illness, characterized by a mild fever and severe headache, without the skin rash common to other spotted fever group Rickettsia species. Members of this genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens. In both groups, the bacteria are transmitted via an insect, usually a tick, to a host organism where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms.