Query: NC_012987:32296 Methylobacterium extorquens DM4 plasmid p1METDI, complete sequence Lineage: Methylobacterium extorquens; Methylobacterium; Methylobacteriaceae; Rhizobiales; Proteobacteria; Bacteria General Information: Methylobacterium extorquens DM4 was isolated from soil contaminated with halogenated (chlorine-containing) hydrocarbons. This organism is able to use dichloromethane as a sole carbon and energy source. Dichloromethane, an industrial solvent, is toxic and carcinogenic. This compound is water soluble and can easily contaminate groundwater. Methylobacterium chloromethanicum was isolated from soil at a petrochemical factory in Tatarstan, Russia. This organism is able to grow using chloromethane as the sole carbon and energy source.
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General Information: This organism is found in both soil and water and has great potential for use in bioremediation as it is capable of degrading a large list of pollutants including chlorinated aromatic compounds. The bacterium can utilize hydrogen, carbon dioxide, as well as organic compounds for growth and is a model organism for hydrogen oxidation as it can grow on hydrogen as the sole energy source. It was originally isolated due to its ability to degrade the herbicide 2,4-dichlorophenoxyacetic acid, which is due to the degradative functions being encoded on a plasmid (pJP4). Metabolically versatile bacterium. Cupriavidus necator also known as Ralstonia eutropha is a soil bacterium with diverse metabolic abilities. Strains of this organism are resistant to high levels of copper or are able to degrade chloroaromatic compounds such as halobenzoates and nitrophenols making them useful for bioremediation.