Query: NC_012925:275704 Streptococcus suis P1/7, complete genome
Lineage: Streptococcus suis; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria
General Information: Streptococcus suis is a pathogen of pigs and is responsible for a variety of diseases including meningitis, arthritis and pneumonia. These infections can have substantial economic impact within the swine industry. Occasionally this organism can infect humans causing septicemia, meningitis and endocarditis. Streptococci are Gram-positive, nonmotile, nonsporeforming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes.
Subject: NC_000963:205546 Rickettsia prowazekii str. Madrid E, complete genome
Lineage: Rickettsia prowazekii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria
General Information: This strain is an egg-passaged attentuated avirulent strain that has been used as a live vaccine and was originally isolated from a typhus patient in Madrid. This species is the causal agent of typhus. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host.