Pre_GI: SWBIT SVG BLASTP

Query: NC_012917:1506083 Pectobacterium carotovorum subsp. carotovorum PC1, complete genome

Lineage: Pectobacterium carotovorum; Pectobacterium; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Temp: Mesophile; Habitat: Host. Pectobacterium carotovorum causes soft-rot diseases of various plant hosts through degradation of the plant cell walls. Formerly Erwinia, these organisms are plant-specific pathogens that invade the vascular systems of plants. Pectobacterium colonize the intercellular spaces of plant cells and deliver potent effector molecules (Avr - avirulence) through a type III secretion system (Hrp - hypersensitive response and pathogenicity). Avr proteins control host-bacterium interactions, including host range. Expression of the plant cell-wall-degrading enzymes is controlled through a quorum-sensing mechanism that quantifies the number of Pectobacterium bacteria through measurement of the concentration of small molecules (acyl homoserine lactones) produced by Pectobacterium.

Subject: NC_008835:1827905 Burkholderia mallei NCTC 10229 chromosome I, complete sequence

Lineage: Burkholderia mallei; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: Causes glanders in horses. This organism is rarely associated with human infection, and is more commonly seen in domesticated animals such as horses, donkeys, and mules where it causes glanders, a disease first described by Aristotle. The pathogen is host-adapted and is not found in the environment outside of its host. Rapid-onset pneumonia, bacteremia (spread of the organism through the blood), pustules, and death are common outcomes during infection. No vaccine exists for this potentially dangerous organism.