Query: NC_012846:1467446 Bartonella grahamii as4aup, complete genome
Lineage: Bartonella grahamii; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria
General Information: Bartonella grahamii (strain as4aup) is Gram-negative bacterium isolated from a wood mouse (Apodemus sylvaticus) in central Sweden. Bartonella are human and animal pathogens which infect erythrocytes and can cause angiogenic lesions. These organisms cause diseases in humans such as Oroya fever, Trench fever, endocarditis, and Cat Scratch disease. Transmission of this organism is via the bite of a blood-sucking arthropod. Bartonella grahamii can be isolated from the blood of rodents and is found world wide. Fleas may be the transmission vector for Bartonella grahamii to other rodents. Human disease appears to be rare and associated with an immunocompromised state.
Subject: NC_009900:1011000 Rickettsia massiliae MTU5, complete genome
Lineage: Rickettsia massiliae; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria
General Information: Rickettsia massiliae MTU5 was isolated from the tick Rhipicephalus turanicus collected from horses in Le Sambuc, Bouches-du Rhone, France. Members of this genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens. In both groups, the bacteria are transmitted via an insect, usually a tick, to a host organism where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Rickettsia massiliae is a member of the spotted fever group of the Rickettsiales and has been isolated from ticks in Europe and Africa. Rickettsia massiliae does not appear to cause disease in humans.