Query: NC_012808:594000 Methylobacterium extorquens AM1, complete genome Lineage: Methylobacterium extorquens; Methylobacterium; Methylobacteriaceae; Rhizobiales; Proteobacteria; Bacteria General Information: First isolated in 1960 in Oxford, England, as an airborne contaminant growing on methylamine. This strain can grow on methylamine or methanol, but not methane. This organism is capable of growth on one-carbon compounds such as methanol. Methanol is oxidized to formaldehyde which is then used metabolically to generate either energy or biomass. These bacteria are commonly found in the environment, especially associated with plants which produce methanol when metabolizing pectin during cell wall synthesis. At least 25 genes are required for this complex process of converting methanol to formaldehyde and this specialized metabolic pathway is of great interest.
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General Information: The cyanobacterium Synechococcus sp. PCC 7002 (formerly known as Agmenellum quadruplicatum strain PR-6) was originally isolated in 1961 by Chase Van Baalen from an onshore, marine mud flat sample derived from fish pens on Maguyes Island, La Parguera, Puerto Rico. The organism grows in brackish (euryhaline/marine) water and is unicellular but tends to form short filaments of two to four cells during exponential growth at the temperature optimum of 38 degrees C. The strain is extremely tolerant of high light intensities and has been grown at light intensities equivalent to two suns. This unique combination of physiological and genetic properties have long made this strain an important model system to studies of the oxygenic photosynthetic apparatus, the regulation of carbon and nitrogen metabolism, and other aspects of cyanobacterial physiology and metabolism.