Query: NC_012808:420334 Methylobacterium extorquens AM1, complete genome Lineage: Methylobacterium extorquens; Methylobacterium; Methylobacteriaceae; Rhizobiales; Proteobacteria; Bacteria General Information: First isolated in 1960 in Oxford, England, as an airborne contaminant growing on methylamine. This strain can grow on methylamine or methanol, but not methane. This organism is capable of growth on one-carbon compounds such as methanol. Methanol is oxidized to formaldehyde which is then used metabolically to generate either energy or biomass. These bacteria are commonly found in the environment, especially associated with plants which produce methanol when metabolizing pectin during cell wall synthesis. At least 25 genes are required for this complex process of converting methanol to formaldehyde and this specialized metabolic pathway is of great interest.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: This strain is a common strain associated with mastitis in cattle. This organism is responsible for several hundred million dollars worth of annual economic loss to animal production each year. Staphylcocci are generally found inhabiting the skin and mucous membranes of mammals and birds. Some members of this genus can be found as human commensals and these are generally believed to have the greatest pathogenic potential in opportunistic infections. This organism is a major cause of nosocomial (hospital-acquired) and community-acquired infections. S. aureus continues to be a major cause of mortality and is responsible for a variety of infections including, boils, furuncles, styes, impetigo and other superficial skin infections in humans. Also known to cause more serious infections particularly in the chronically ill or immunocompromised. The ability to cause invasive disease is associated with persistance in the nasal cavity of a host.