Query: NC_012808:1220378 Methylobacterium extorquens AM1, complete genome Lineage: Methylobacterium extorquens; Methylobacterium; Methylobacteriaceae; Rhizobiales; Proteobacteria; Bacteria General Information: First isolated in 1960 in Oxford, England, as an airborne contaminant growing on methylamine. This strain can grow on methylamine or methanol, but not methane. This organism is capable of growth on one-carbon compounds such as methanol. Methanol is oxidized to formaldehyde which is then used metabolically to generate either energy or biomass. These bacteria are commonly found in the environment, especially associated with plants which produce methanol when metabolizing pectin during cell wall synthesis. At least 25 genes are required for this complex process of converting methanol to formaldehyde and this specialized metabolic pathway is of great interest.
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General Information: Bacterium that undergoes asymmetric cell division and differentiation. Caulobacter vibroides, also known as Caulobacter crescentus, inhabits aquatic environments and plays an important part in biogeochemical cycling of organic nutrients. This bacterium undergoes an unusual developmental cycle in which a swarming motile cell becomes a stalked cell that is attached to a solid surface. The stalked cell then undergoes asymmetric cell division and produces one flagellated motile daughter cell and one stalked daughter cell. Thus, the asymmetric processes in this organism provide useful models for differentiation and development. This organism also contains a number of energy-dependent transport system, presumably enabling growth in the substrate-sparse aquatic environments that it lives in.