Query: NC_012779:1286500 Edwardsiella ictaluri 93-146, complete genome Lineage: Edwardsiella ictaluri; Edwardsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria General Information: Edwardsiella ictaluri is the causative agent of enteric septicemia in catfish (ESC), an economically significant disease of farm-raised catfish. The acute form of ESC causes bacterial septicemia (proliferation of bacteria in the blood) which rapidly leads to death. The chronic form of this disease causes a characteristic head lesion, and may also proceed to septicemia and death. Two plasmids, which are consistently present in Edwardsiella ictaluri isolates, have been sequenced. Both plasmids contain genes for the type III secretory system, which is involved in translocating pathogenicity proteins into the eukaryotic cell.
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General Information: Causes glanders in horses. This organism is rarely associated with human infection, and is more commonly seen in domesticated animals such as horses, donkeys, and mules where it causes glanders, a disease first described by Aristotle. The pathogen is host-adapted and is not found in the environment outside of its host. Rapid-onset pneumonia, bacteremia (spread of the organism through the blood), pustules, and death are common outcomes during infection. No vaccine exists for this potentially dangerous organism.