Query: NC_012724:829830 Burkholderia glumae BGR1 chromosome 1, complete genome Lineage: Burkholderia glumae; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria General Information: Burkholderia glumae causes seedling rot and panicle blight of rice. Panicle blight is a significant problem in the southern USA during unusually warm growing seasons. Infection of rice with Burkholderia glumae causes sterility, or abortion, of the rice kernels, and may inhibit seed germination. Burkholderia glumae also produces an industrially important extracellular lipase.
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General Information: This strain (UTI89) is a uropathogenic strain isolated from a woman with uncomplicated cystitis (bladder inflammation) that has been demonstrated to cause cystitis in a murine urinary tract infection model. This organism was named for its discoverer, Theodore Escherich, and is one of the premier model organisms used in the study of bacterial genetics, physiology, and biochemistry. This enteric organism is typically present in the lower intestine of humans, where it is the dominant facultative anaerobe present, but it is only one minor constituent of the complete intestinal microflora. E. coli, is capable of causing various diseases in its host, especially when they acquire virulence traits. E. coli can cause urinary tract infections, neonatal meningitis, and many different intestinal diseases, usually by attaching to the host cell and introducing toxins that disrupt normal cellular processes.