Query: NC_012633:276500 Rickettsia africae ESF-5, complete genome
Lineage: Rickettsia africae; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria
General Information: This organism was isolated from a cattle tick, Amblyomma variegatum, collected in Ethiopia. This organism, a member of the spotted fever group of the Rickettsiales, is found in sub-Saharan Africa and the Caribbean. Rickettsia africae causes a flu-like illness, characterized by a mild fever and severe headache, without the skin rash common to other spotted fever group Rickettsia species. Members of this genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens. In both groups, the bacteria are transmitted via an insect, usually a tick, to a host organism where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms.
Subject: NC_005861:2120633 Candidatus Protochlamydia amoebophila UWE25, complete genome
Lineage: Protochlamydia amoebophila; Protochlamydia; Parachlamydiaceae; Chlamydiales; Chlamydiae; Bacteria
General Information: An endosymbiont of free-living amoebae (Acanthamoeba sp. endosymbiont UWE25) and implicated as a potential human pathogen this strain is an environmental isolate. Amoeba endosymbiont. Bacteria belonging to the Chlamydiales group are obligate intracellular parasites of eukaryotic cells. They are found within vertebrates, invertebrate cells, and amoebae hosts. Chlamydiae are one of the commonest causes of sexually transmitted diseases (STDs) and if left untreated may cause infertility in women. They are transmitted by direct contact or aerosols, and can cause various diseases, while also being able to coexist with the host in an apparently asymptomatic state. Candidatus Protochlamydia amoebophila, originally Parachlamydia is an endosymbiont of free-living amoebae (Acanthamoeba). This organism is an obligate intracellular endosymbiont and lives in small inclusions dispersed throughout the host cell.