Pre_GI: SWBIT SVG BLASTP

Query: NC_012632:1212780 Sulfolobus islandicus M.16.27 chromosome, complete genome

Lineage: Sulfolobus islandicus; Sulfolobus; Sulfolobaceae; Sulfolobales; Crenarchaeota; Archaea

General Information: This strain was isolated from a hot spring on the Kamchatka Penninsula, in the Russian Far East. Hyperthermophilic acidophilic sulfur-metabolizing archeon. Sulfolobus islandicus is a thermo-acidophilic archeae commonly identified in hot, acidic sulfur springs. This organism can grow both chemoautotrophically, using sulfur or hydrogen sulfide, and heterotrophically. S. islandicus can play host to a number of plasmids and viruses which may be useful in developing tools for genetic analysis. In addition, Sulfolobus islandicus isolates from different areas in Russia, Iceland, and the United States have been shown to be genetically distinct from each other making this organism useful for comparative analysis.

Subject: NC_008343:2020785 Granulibacter bethesdensis CGDNIH1, complete genome

Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria

General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.