Query: NC_012471:51305 Streptococcus equi subsp. equi 4047, complete genome Lineage: Streptococcus equi; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria General Information: Streptococcus equi equi is an obligate parasitic bacterium and is the causative agent of a serious upper respiratory tract disease within members of the family Equidae (horses), called strangles. Strangles is a highly contagious disease of the nasopharynx and lymph nodes. The genome sequence of this organism will provide information into the production and regulation of virulence factors involved in this disease. Pathogenic in horses, goats and sheep. Streptococci are Gram-positive, nonmotile, nonsporeforming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes.
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General Information: This strain is used in laboratory studies of bronchopneumonia in swine. Causes enzootic pneumonia in swine. This genus currently comprizes more than 120 obligate parasitic species found in the wide spectrum of hosts, including humans, animals, insects and plants. The primary habitats of human and animal mycoplasmas are mucouse membranes of the respiratory and urogenital tracts, eyes, mammary glands and the joints. Infection that proceeds through attachment of the bacteria to the host cell via specialized surface proteins, adhesins, and subsequent invation, results in prolonged intracellular persistence that may cause lethality. Once detected in association with their eukaryotic host tissue, most of mycoplasmas can be cultivated in the absence of a host if their extremely fastidious growth requirements are met.