Pre_GI: SWBIT SVG BLASTP

Query: NC_012416:531772 Wolbachia sp. wRi, complete genome

Lineage: Wolbachia; Wolbachia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Endosymbiont. Obligate intracellular bacterium infects around 20% of all insect species. Naturally infects Drosophila simulans and induces almost complete cytoplasmic incompatibility in its host. Wolbachia sp. subsp. Drosophila simulans (strain wRi) is an intracellular proteobacterium that infect insects as well as isopods, spiders, scorpions, mites, and filarial nematodes. It is maternally inherited and induces reproductive alterations of insect populations by male killing, feminization, parthenogenesis, or cytoplasmic incompatibility. In insect populations, Wolbachia sp. induce reproductive manipulations to enhance their own spreading. The most frequently observed reproductive abnormality is cytoplasmic incompatibility, where uninfected females are unable to produce offspring with infected males, whereas infected females can produce offspring with both infected and uninfected males, thus creating a reproductive advantage for infected females. Other spectacular effects of Wolbachia sp. infections are male embryo killing, feminization, and parthenogenesis induction.

Subject: NC_014760:419692 Mycoplasma bovis PG45 chromosome, complete genome

Lineage: Mycoplasma bovis; Mycoplasma; Mycoplasmataceae; Mycoplasmatales; Tenericutes; Bacteria

General Information: This bacterium causes a contagious disease of cattle causing respiratory disease, mastitis, and arthritis. It is found worldwide and is inherently resistant to certain groups of antibiotics because it does not possess a cell wall. More recently, this species has become resistant to tetracycline, tilmicosin and spectinomycin which have been traditionally used in its control. The disease is spread between herds by the transfer of infected but seemingly healthy animals which shed viruses. It has also been introduced into healthy herds via frozen semen collected from an infected bull. The economic losses and negative impact on international trade from this disease have been considerable, and efforts are now underway to develop a vaccine.