Pre_GI: SWBIT SVG BLASTP

Query: NC_012207:2573562 Mycobacterium bovis BCG str. Tokyo 172, complete genome

Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.

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BLASTP Alignment.txt

Subject: NC_013159:1422370 Saccharomonospora viridis DSM 43017, complete genome

Lineage: Saccharomonospora viridis; Saccharomonospora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This organism has been implicated in a range of hypersensitivity pneumonitides, including farmer's lung disease. Symptoms of the disease develop in susceptible individuals following the inhalation of spores from overheated materials such as moldy hay and bagasse, or from forced-air heating and humidification systems. Prolonged exposure to the antigens results in acute respiratory distress which may lead to irreversible lung damage. Saccharomonospora viridis DSM 43017 was isolated from Irish peat and was originally classified as Thermomonospora viridis.