Pre_GI: SWBIT SVG BLASTP

Query: NC_012207:2573562 Mycobacterium bovis BCG str. Tokyo 172, complete genome

Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.

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BLASTP Alignment.txt

Subject: NC_010804:2206000 Burkholderia multivorans ATCC 17616 chromosome 1, complete

Lineage: Burkholderia multivorans; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: Isolated from soil enriched with anthranilate at 41C, Berkeley, CA, USA. This species is associated with infections in cystic fibrosis patients. It is an important opportunistic pathogen, colonizing the lungs and associated with a decrease in long-term survival. This species is a member of the Burkholderia cepacia complex, although it does not appear to spread from patient to patient as do the other members of the group.