Query: NC_012108:5273289 Desulfobacterium autotrophicum HRM2, complete genome Lineage: Desulfobacterium autotrophicum; Desulfobacterium; Desulfobacteraceae; Desulfobacterales; Proteobacteria; Bacteria General Information: It was isolated from a marine sediment in the Mediterranean sea near Venice, Italy. It is involved in the anaerobic mineralization of organic matter coming from the water column. Desulfobacterium autotrophicum is capable of growing litho-autotrophically with H2, CO2 and sulfate, but also by coupling sulfate reduction with the oxidation of fatty acids. This organism can transform tetra to dichlormethane.
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General Information: Clostridium difficile R20291 was isolated in Stoke Mandeville Hospital, UK in 2006 and is closely related to the North American hypervirulent BI strains. Clostridium difficile, a Gram-positive, spore-forming anaerobic bacterium, is the leading cause of infectious diarrhea among patients in hospitals worldwide, causing C. difficile infection (CDI). An important nosocomial pathogen, it is frequently associated with antibiotic treatment and causes diseases ranging from antibiotic-associated diarrhea to life-threatening pseudomembraneous colitis.