Query: NC_012039:1399699 Campylobacter lari RM2100, complete genome Lineage: Campylobacter lari; Campylobacter; Campylobacteraceae; Campylobacterales; Proteobacteria; Bacteria General Information: Causes gastrointestinal disease. This organism is closely related to C. jejuni and C. coli and is a foodborne pathogen that causes gastroenteritis and diarrhea. In addition this organism can cause bacteremia and septicemia in immunocompromised individuals. The bacterium is found in a variety of habitats including water environments, and seagulls are considered a reservoir for the organism. Shellfish can harbor the organism when inhabiting water contaminated by seagulls carrying the organism.
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General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.