Query: NC_012034:438000 Anaerocellum thermophilum DSM 6725, complete genome Lineage: Caldicellulosiruptor bescii; Caldicellulosiruptor; Thermoanaerobacterales Family III; Thermoanaerobacterales; Firmicutes; Bacteria General Information: Anaerocellum thermophilum was isolated from a hot spring on the Kamchatka peninsula in Russia. This organism produces thermostable enzymes which can degrade cellulose and starches and may be of use in industry.
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General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.