Query: NC_011978:493800 Thermotoga neapolitana DSM 4359, complete genome Lineage: Thermotoga neapolitana; Thermotoga; Thermotogaceae; Thermotogales; Thermotogae; Bacteria General Information: This hyperthermophilic organism was first isolated from a black smoker in the bay near Naples, Italy in 1986. This organism, like other Thermotoga, produces a vast quantity of hydrogen in batch culture. It is being considered for use in projects to utilize waste carboydrates for the production of hydrogen gas for industrial purposes. A number of thermostable enzymes such as alkaline phosphatase are also produced by this bacterium and may be of use for industrial purposes.
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General Information: This strain was isolated in 1989 in North Carolina, USA from a 2-year-old male dog. This organisms causes canine monocytic ehrlichiosis, which is a tick-born disease that causes severe morbidity in domesticated and wild dogs. The brown dog tick, Rhipicephalus sanguineus, transfers the organism from its salivary glands to the animal when feeding. Persistence in the vacuole leads to replication and cell division and eventual release from the cell which leads to further spreading of the bacterium throughout the host. The end result is an increase in platelet count and anemia.