Pre_GI: SWBIT SVG BLASTP

Query: NC_011959:815601 Thermomicrobium roseum DSM 5159, complete genome

Lineage: Thermomicrobium roseum; Thermomicrobium; Thermomicrobiaceae; Thermomicrobiales; Chloroflexi; Bacteria

General Information: Thermomicrobium roseum DSM 5159 was isolated from Yellowstone National Park, USA. Obligate thermophile with unusual cell wall structure. Thermomicrobium roseum is a red-pigmented, rod-shaped, Gram-negative extreme thermophile that possesses both an atypical cell wall composition and an unusual cell membrane that is composed entirely of long-chain 1,2-diols. Analyses of environmental sequences from hot spring environments show that T.roseum displays a low quantity but ubiquitous presence in top layers of microbial mats. Few standard housekeeping genes are found on the megaplasmid, however, it does encode a complete system for chemotaxis including both chemosensory components and an entire flagellar apparatus. T. roseum oxidizes CO aerobically, making it the first thermophile known to do so. In addition, is is propose that glycosylation of its carotenoids plays a crucial role in the adaptation of the cell membrane to this bacterium's thermophilic lifestyle. Because T. roseum is a deep-branching member of this phylum, eventhough this species is not photosynthetic, analysis of the genome provides some insight into the origins of photosynthesis in the Chloroflexi.

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BLASTP Alignment.txt

Subject: NC_006361:1547034 Nocardia farcinica IFM 10152, complete genome

Lineage: Nocardia farcinica; Nocardia; Nocardiaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This type strain was isolated from the bronchus of a male Japanese patient. Opportunistic human pathogen. This genus was originally described from specimens isolated by plating soil suspensions on diagnostic sensitivity test plates augmented with antifungal agents. Organisms in this genus cause opportunistic human pulmonary and systemic nocardiosis. This can complicate existing debilitating conditions such as leukemia, lymphoma, or other neoplasms, or illnesses in patients with compromised immune systems.