Query: NC_011958:1031592 Rhodobacter sphaeroides KD131 chromosome 2, complete genome Lineage: Rhodobacter sphaeroides; Rhodobacter; Rhodobacteraceae; Rhodobacterales; Proteobacteria; Bacteria General Information: Bacteria belonging to the Rhodobacter group are metabolically versatile as they are able to grow using photosynthesis, chemosynthesis, and usually can grow under both anaerobic and aerobic conditions. The most extensively studied bacteria with regards to its photosynthetic capabilities which includes the structure, function and regulation of its photosynthetic membranes, its mechanisms of CO2 and nitrogen fixation, cytochrome diversity and its electron transport systems. It can grow aerobically and anaerobically in the light and anaerobically in the dark. It produces an intracytoplasmic membrane system consisting of membrane invaginations where the light harvesting complexes (LH1 and LH2) and the reaction center are synthesized. Furthermore, it has the ability to detoxify metal oxides and oxyanions and hence has a role in bioremediation.
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General Information: Lawsonia intracellularis PHE/MN1-00 was isolated from intestinal mucosal lesions in pigs that had proliferative enteropathy (PE). When introduced into health pigs, this organism produced the clinical and histological signs of PE. Causative agent for proliferative enteropathy in swine. This organism causes proliferative enteropathy (ileitis) in swine and other domesticated animals resulting in severe losses each year. This obligate intracellular pathogen infects the mucosa of the lower intestinal tract by initially infecting crypt cells, which are precursors that normally grow and divide in order to replace the epithelial cells. Once infection occurs, the crypt cells are stimulated to grow and divide abnormally, resulting in the proliferative phenotype. In severe cases of the disease the entire bowel can become affected and persist for up to 40 days, greatly affecting the host animal.