Pre_GI: SWBIT SVG BLASTP

Query: NC_011916:2967624 Caulobacter crescentus NA1000 chromosome, complete genome

Lineage: Caulobacter vibrioides; Caulobacter; Caulobacteraceae; Caulobacterales; Proteobacteria; Bacteria

General Information: Caulobacter crescentus NA1000 is a spontaneous mutant derivative of C. crescentus strain CB15. It is used by labs worldwide because it can easily be synchronized, allowing for studies of the bacterial cell cycle. Caulobacter vibroides, also known as Caulobacter crescentus, inhabits aquatic environments and plays an important part in biogeochemical cycling of organic nutrients. This bacterium undergoes an unusual developmental cycle in which a swarming motile cell becomes a stalked cell that is attached to a solid surface. The stalked cell then undergoes asymmetric cell division and produces one flagellated motile daughter cell and one stalked daughter cell. Thus, the asymmetric processes in this organism provide useful models for differentiation and development. This organism also contains a number of energy-dependent transport system, presumably enabling growth in the substrate-sparse aquatic environments that it lives in.

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Subject: NC_004310:508483 Brucella suis 1330 chromosome I, complete sequence

Lineage: Brucella suis; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: A swine isolate. Causes brucellosis, infectious abortions, fevers. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism is a swine-specific Brucella. It causes infectious abortions in animals and a systemic, febrile (feverish) illness in humans. Brucella suis is considered a potential bioterrorism agent and was the first pathogenic organism to be weaponized by the USA.