Pre_GI: SWBIT SVG BLASTP

Query: NC_011898:2907017 Clostridium cellulolyticum H10, complete genome

Lineage: Clostridium cellulolyticum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: A non-ruminal mesophilic cellulolytic bacterium originally isolated from decayed grass compost. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Clostridium cellulolyticum is a mesophilic cellulolytic bacterium. Cellulose-degradation by C. cellulolyticum has been extensively studied. The cellulolytic enzymes of this organism are bound to a protein scaffold in an extracellular multienzyme complex called a cellulosome.

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BLASTP Alignment.txt

Subject: NC_007517:1468719 Geobacter metallireducens GS-15, complete genome

Lineage: Geobacter metallireducens; Geobacter; Geobacteraceae; Desulfuromonadales; Proteobacteria; Bacteria

General Information: First isolated from the Potomac river downstream of Washington, DC, USA in 1987. This organism actively moves towards metal attractants such as iron and manganese oxides, which are insoluble, and produces type IV pili for attachment to the insoluble substrates. Common metal-reducing bacterium. This organism, similar to what is observed in Geobacteria sulfurreducens, couples the oxidation of organic molecules to the reduction of iron by using insoluble Fe (III) as an electron acceptor under anaerobic conditions. This bacterium plays an imporant part of the nutrient cycling in aquatic environments. The cell can also use uranium and plutonium, therefore, this organism and may be important for the bioremediation of contaminated waste sites.