Query: NC_011894:7563668 Methylobacterium nodulans ORS 2060, complete genome
Lineage: Methylobacterium nodulans; Methylobacterium; Methylobacteriaceae; Rhizobiales; Proteobacteria; Bacteria
General Information: Methylobacterium nodulans was isolated from root nodules from the legume Crotalaria, a large Fabaceae group found in Africa. Methylobacterium nodulans fixes nitrogen and can grow with C1 compounds, such as methanol and formate, as a sole carbon source.
Subject: NC_003116:291661 Neisseria meningitidis Z2491, complete genome
Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria
General Information: This is a serogroup A strain isolated in Gambia in 1983. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.