Query: NC_011886:2696671 Arthrobacter chlorophenolicus A6, complete genome Lineage: Arthrobacter chlorophenolicus; Arthrobacter; Micrococcaceae; Actinomycetales; Actinobacteria; Bacteria General Information: Arthrobacter chlorophenolicus A6 (DSM 12829) was isolated from soil at Fort Collins, Colorado, USA and is able to use 4-chlorophenol as a sole source of carbon and energy. This organism can degrade 4-chlorophenol in soil at temperatures ranging from 5 to 28 degrees C making it a good candidate for bioremediation. Arthrobacter chlorophenolicus can degrade high concentrations of para-substituted phenols, such as 4-chlorophenol and 4-nitrophenol and can survive under harsh conditions, such as cold temperature and during starvation in soil.
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General Information: This strain was isolated from a patient in 1994. Opportunistic pathogen that causes multiple hospital-acquired infections. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.