Query: NC_011837:830436 Clostridium kluyveri NBRC 12016, complete genome Lineage: Clostridium kluyveri; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria General Information: Involved in production of caproic acid in co-culture with a methanogen. Clostridium kluyveri was enriched from mud in a co-culture with Methanobacterium omelianskii. When grown on ethanol C. kluyveri produce caproic acid in addition to acetic acid. This organism is able to grow anaerobically on ethanol and acetate as sole energy sources.
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General Information: A swine isolate. Causes brucellosis, infectious abortions, fevers. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism is a swine-specific Brucella. It causes infectious abortions in animals and a systemic, febrile (feverish) illness in humans. Brucella suis is considered a potential bioterrorism agent and was the first pathogenic organism to be weaponized by the USA.