Query: NC_011768:4571869 Desulfatibacillum alkenivorans AK-01, complete genome Lineage: Desulfatibacillum alkenivorans; Desulfatibacillum; Desulfobacteraceae; Desulfobacterales; Proteobacteria; Bacteria General Information: Desulfatibacillum alkenivorans AK-01 was isolated from sediment from the Arthur Kill, NJ/NY waterway, USA. This site has a history of contamination from petrochemical industry and strain AK-01 is able to degrade 13 to 18 carbon alkanes. Desulfatibacillum alkenivorans is an alkene-degrading, sulfate-reducing bacterium isolated from estuarine sediment. It activates alkanes via subterminal addition of the alkane to fumarate.
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General Information: This strain was isolated from an infected goat and is pathogenic in humans. Causes brucellosis and undulant fever. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism is a facultative intracellular bacteria that causes abortion in wild and domestic animals, usually goats or sheep, and undulant fever in humans. Brucellosis is a major health problem in the Mediterranean region and parts of Asia, Africa, and Latin America, where it causes severe economic losses. The disease is transmitted to humans by nonpasteurized milk and milk products or by direct contact with infected animals or carcasses.