Query: NC_011761:2457560 Acidithiobacillus ferrooxidans ATCC 23270 chromosome, complete Lineage: Acidithiobacillus ferrooxidans; Acidithiobacillus; Acidithiobacillaceae; Acidithiobacillales; Proteobacteria; Bacteria General Information: This organism was isolated from bituminous coal mine effluent. Acidophilic iron-oxidizing bacterium. Acidithiobacillus ferrooxidans, formerly Thiobacillus ferrooxidans, is an acidophilic iron-oxidizing bacterium that is able to grow at a pH range of 1.3 to 4.0. This organism is often identified in acid mine drainage and as a member of microbial consortia involved in bioleaching. Acidithiobacillus ferrooxidans has been identified as the dominant microorganism in percolation and continuous flow mineral leaching bioreactors.
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General Information: Causes bovine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism was first noticed on the island of Malta by Dr. David Bruce during an epidemic among British soldiers. It is the primary cause of bovine brucellosis, which results in enormous (billions of dollars) economic losses due primarily to reproductive failure and food losses. In man, it causes undulant fever, a long debilitating disease that is treated by protracted administration of antibiotics.