Query: NC_011658:4171237 Bacillus cereus AH187 chromosome, complete genome Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria General Information: This strain was isolated from the vomit of a person having eaten cooked rice by the Public Health Laboratory Service (PHLS), London, UK. The isolate was associated with an emetic outbreak in 1972. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.
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General Information: Streptococcus pneumoniae Hungary19A-6 is a penicillin resistant strain. This organism is a member of the normal human nasopharyngeal flora. There are more than 85 different antigenic types of S. pneumoniae, which are classified based on their capsule antigens. This organism is also the most common cause of sinusitis, acute bacterial otitis media, and conjunctivitis beyond early childhood. S. pneumoniae is also known to cause pneumonia, meningitis, and bacteremia. Streptococci are Gram-positive, non-motile, non-spore forming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Serologic grouping is based on antigenic differences in cell wall carbohydrates, in cell wall pili-associated protein, and in the polysaccharide capsule in group B streptococci.