Query: NC_011567:204772 Anoxybacillus flavithermus WK1, complete genome Lineage: Anoxybacillus flavithermus; Anoxybacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria General Information: Anoxybacillus flavithermus, formerly Bacillus flavothermus, was isolated from a hot spring in New Zealand. This organism can tolerate a pH of up to 9.0. Gram-positive bacteria of the genus Anoxybacillus have been found in diverse thermophilic habitats, such as geothermal hot springs and manure, and in processed foods such as gelatin and milk powder.
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General Information: This strain was isolated in 1989 in North Carolina, USA from a 2-year-old male dog. This organisms causes canine monocytic ehrlichiosis, which is a tick-born disease that causes severe morbidity in domesticated and wild dogs. The brown dog tick, Rhipicephalus sanguineus, transfers the organism from its salivary glands to the animal when feeding. Persistence in the vacuole leads to replication and cell division and eventual release from the cell which leads to further spreading of the bacterium throughout the host. The end result is an increase in platelet count and anemia.