Pre_GI: SWBIT SVG BLASTP

Query: NC_011283:942594 Klebsiella pneumoniae 342 chromosome, complete genome

Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Klebsiella pneumoniae 342 was isolated from the stem tissue of Zea mays. This strain fixes atmospheric nitrogen and may be able to provide nitrogen, in the form of ammonia, to plant cells. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

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BLASTP Alignment.txt

Subject: NC_008783:1101973 Bartonella bacilliformis KC583, complete genome

Lineage: Bartonella bacilliformis; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Cauative agent of Carrion's disease. Like other members of this genus, Bartonella bacilliformis is an obligate intracellular parasite, which infects red blood cells. Bartonella bacilliformis is the causative agent of Carrion's disease, also called Oroya fever. This disease is found in the western Andes of South America, and is transmitted through an insect vector. Carrion's disease is characterized by an acute, febrile, anemia with a mortality of 40 to 90%. The anemic phase may be followed by a milder secondary episode, characterized by wart-like skin lesions.