Pre_GI: SWBIT SVG BLASTP

Query: NC_011244:746801 Borrelia recurrentis A1, complete genome

Lineage: Borrelia recurrentis; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: Borrelia recurrentis isolated from adult patient with louse-borne relapsing fever in Ethiopia. Borrelia recurrentis is the causative agent of louse-borne relapsing fever. Prior to World War II, this organism was responsible for large disease outbreaks with a mortality of up to 40% in much of the world. Currently this disease is limited to parts of Africa, China, and Peru. B. recurrentis is transmitted when infected human body lice (Pediculus humanus) are crushed and their fluids contaminate mucous membranes or breaks in the skin. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another.

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BLASTP Alignment.txt

Subject: NC_009850:1011293 Arcobacter butzleri RM4018, complete genome

Lineage: Arcobacter butzleri; Arcobacter; Campylobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: Arcobacter butzleri RM4018 was isolated from a human patient with gastroenteritis. Causes gastroenteritis in humans. Arcobacter butzleri is a member of the family Campylobacteraceae, related to the human pathogenic Campylobacter spp. and the environmental Sulfurospirillum spp. A. butzleri is mainly found in livestock and water/marine environments and can cause gastroenteritis and bacteremia in humans.