Query: NC_011206:2369500 Acidithiobacillus ferrooxidans ATCC 53993, complete genome Lineage: Acidithiobacillus ferrooxidans; Acidithiobacillus; Acidithiobacillaceae; Acidithiobacillales; Proteobacteria; Bacteria General Information: Acidithiobacillus ferrooxidans, formerly Thiobacillus ferrooxidans, is an acidophilic iron-oxidizing bacterium that is able to grow at a pH range of 1.3 to 4.0. This organism is often identified in acid mine drainage and as a member of microbial consortia involved in bioleaching. Acidithiobacillus ferrooxidans has been identified as the dominant microorganism in percolation and continuous flow mineral leaching bioreactors.
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General Information: This strain was isolated in 1997 from the pharyngeal membrane of a 72-year-old unimmunized UK female with clinical diphtheria acquired during a short Baltic cruise. Causative agent of diphtheria. They may be found as members of the normal microflora of humans, where these bacteria find a suitable niche in virtually every anatomic site. This organism is the best known and most widely studied species of the genus. It is the causal agent of the disease diphtheria, a deadly infectious disease spreading from person to person by respiratory droplets from the throat through coughing and sneezing. In the course of infection, the bacteria invade and colonize tissues of the upper respiratory tract, proliferate and produce exotoxin that inhibits protein synthesis and causes local lesions and systemic degenerative changes in the heart, muscles, peripheral nerves, liver and other vital organs. In 1951, Victor Freeman discovered that pathogenic (toxigenic) strains. Moreover, later it was found that the gene for toxin production is located in the DNA of the B-type phage.