Pre_GI: SWBIT SVG BLASTP

Query: NC_011205:3942500 Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853

Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This is a bovine-adapted serovar that is genetically related to S. Enteritidis that lives in the bovine intestinal tract and can causes disease in humans. While rare in incidence, S. dublin infection classically produces a syndrome of sustained bacteremia with fever, resulting in high morbidity and mortality. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark);
- hypothetical protein; - cds: hover for description

BLASTP Alignment.txt

Subject: NC_009079:2339756 Burkholderia mallei NCTC 10247 chromosome I, complete sequence

Lineage: Burkholderia mallei; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: Isolated in 1960 in Turkey. Causes glanders in horses. This organism is rarely associated with human infection, and is more commonly seen in domesticated animals such as horses, donkeys, and mules where it causes glanders, a disease first described by Aristotle. This organism is similar to B. pseudomallei and is differentiated by being nonmotile. The pathogen is host-adapted and is not found in the environment outside of its host. Rapid-onset pneumonia, bacteremia (spread of the organism through the blood), pustules, and death are common outcomes during infection. No vaccine exists for this potentially dangerous organism.