Query: NC_011147:4460726 Salmonella enterica subsp. enterica serovar Paratyphi A str Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria General Information: This strain is a clinical isolate collected from a child with paratyphoid fever in Karachi, Pakistan, 2004. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.
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General Information: First isolated from the Potomac river downstream of Washington, DC, USA in 1987. This organism actively moves towards metal attractants such as iron and manganese oxides, which are insoluble, and produces type IV pili for attachment to the insoluble substrates. Common metal-reducing bacterium. This organism, similar to what is observed in Geobacteria sulfurreducens, couples the oxidation of organic molecules to the reduction of iron by using insoluble Fe (III) as an electron acceptor under anaerobic conditions. This bacterium plays an imporant part of the nutrient cycling in aquatic environments. The cell can also use uranium and plutonium, therefore, this organism and may be important for the bioremediation of contaminated waste sites.