Pre_GI: SWBIT SVG BLASTP

Query: NC_011147:2085241 Salmonella enterica subsp. enterica serovar Paratyphi A str

Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is a clinical isolate collected from a child with paratyphoid fever in Karachi, Pakistan, 2004. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

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BLASTP Alignment.txt

Subject: NC_007164:511171 Corynebacterium jeikeium K411, complete genome

Lineage: Corynebacterium jeikeium; Corynebacterium; Corynebacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from the axilla of a bone marrow transplant patient. A serious nocosomial pathogen. This bacterium is a lipophilic and multidrug resistant member of the human skin flora. This species has been associated with bacterial endocarditis following cardiac surgery. Other nocosomial infections involving this organism are associated with immunocompromised patients with malignancies, in-place medical devices, breaks in the skin barrier, and therapy with broad-spectrum antibiotics.