Pre_GI: SWBIT SVG BLASTP

Query: NC_011094:688626 Salmonella enterica subsp. enterica serovar Schwarzengrund str

Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This serovar is the predominant cause of Salmonellosis in Southeast Asia, a major source of imported food products to the USA. It was also the cause of the first recognized outbreak of fluoroquinolone-resistant salmonellosis in the USA. Recent reports suggest that high-level fluoroquinolone resistance is emerging in S. Schwarzengrund in different parts of the world. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

Subject: NC_020064:2779864 Serratia marcescens FGI94, complete genome

Lineage: Serratia marcescens; Serratia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This organism was discovered in 1819 by Bizio who named the organism after the Italian physicist Serrati. It was considered a nonpathogenic organism until late in the 20th century, although pathogenicity was noted as early as 1913. Serratia marcescens is an opportunistic human pathogen that is increasingly associated with life-threatening hospital-acquired infections. It is an environmental organism that has a broad host range, and is capable of infecting vertebrates and invertebrates, as well as plants. In humans, Serratia marcescens can cause meningitis (inflammation of the membrane surrounding the brain and spinal cord), endocarditis (inflammation of heart muscle) and pyelonephritis (inflammation of the kidneys). Many strains are resistant to multiple antibiotics. Environmental isolates are noted by production of the red pigment prodigiosin.